BiomoleculesAnimalstau ProteinsMiceTransgenicMale
Effect of the Icelandic Mutation APPA673T in the Murine APP Gene on Phenotype of Line 66 Tau Mice.
Anne Anschuetz, Lianne Robinson, Miguel Mondesir, Valeria Melis, Bettina Platt, Charles R Harrington, Gernot Riedel, Karima Schwab
Published: 202510.3390/biom16010028
Abstract
The Icelandic mutation in the amyloid precursor protein (APP), APPA673T, has been identified in Icelandic and Scandinavian populations and is associated with a significantly lower risk of developing Alzheimer's disease (AD). The introduction of the h…
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