BiomoleculesHumansKetone BodiesNeoplasmsCoenzyme A-TransferasesAnimals
The Function and Mechanism of OXCT1 in Tumor Progression as a Critical Ketone Body Metabolic Enzyme.
Wen Qin, Wenwei Hu, Yiting Geng
Published: 202510.3390/biom16010004
Abstract
3-Ketoacid CoA-transferase 1 (OXCT1) is a homodimeric mitochondrial matrix enzyme essential for ketone body metabolism. It catalyzes the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate, playing a central role in extrahepatic keton…
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