Biology
Suppressing Endothelial-Mesenchymal Transition Through the Histone Deacetylase 1/GATA Binding Protein 4 Pathway: The Mechanism of Protocatechuic Acid Against Myocardial Fibrosis Revealed by an Integrated Study.
Chengsi Jin, Chongyu Shao, Guanfeng Xu, Haitong Wan
Published: 202610.3390/biology15020206
Abstract
BACKGROUND: Myocardial fibrosis, a central pathological process leading to heart failure, lacks specific mechanism-based therapies. Although the anti-inflammatory activity of the natural compound protocatechuic acid is recognized, its direct anti-fib…
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