Antioxidants (Basel, Switzerland)
Drosophila Keap1 Proteins Assemble Nuclear Condensates in Response to Oxidative Stress.
Guangye Ji, Bethany Cross, Thomas Killmer, Bee Enders, Emma Neidviecky, Hayden Huber, Grace Lynch, Huai Deng
Published: 202610.3390/antiox15010134
Abstract
The Keap1-Nrf2 signaling pathway is a central regulator of transcriptional responses to oxidative stress and is strongly linked to diverse pathologies, particularly cancer. In the cytoplasm, Keap1 (Kelch-like ECH-associated protein 1) promotes protea…
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