Antioxidants (Basel, Switzerland)
Oxidative Stress and Lysosomal Dysfunction in Neurodegenerative Diseases: Underlying Mechanisms and Nanotherapeutic Targeting Strategies.
Yuhe Hu, Zhaofei Yang, Xu Wang, Xiang Li, Min Wei
Published: 202610.3390/antiox15010073
Abstract
Neurodegenerative diseases (NDDs), defined by the progressive loss of neurons, present a major challenge to global health. Oxidative stress and lysosomal dysfunction are both key pathogenic factors in NDDs, and they do not operate in isolation; inste…
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