Antioxidants (Basel, Switzerland)
Phagocyte NADPH Oxidase NOX2-Derived Reactive Oxygen Species in Antimicrobial Defense: Mechanisms, Regulation, and Therapeutic Potential-A Narrative Review.
George Țocu, Bogdan Ioan Ștefănescu, Loredana Stavăr Matei, Lavinia Țocu
Published: 202510.3390/antiox15010055
Abstract
ROS derived from NADPH oxidase, particularly NOX2, are central to antimicrobial defense, coupling direct pathogen killing with redox signaling that shapes inflammation. This narrative review integrates recent advances on NOX2 structure, assembly, and…
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