Clinical and molecular hepatology
MicroRNA isomiRs reveal novel pathways linked to disease activity and fibrosis in MASLD.
Christian Brion, Stephen A Hoang, Guangliang Wang, Faridodin Mirshahi, Jessie Ang, Matthew R Long, Zheng Zhu, Bhanu Sakhamuri, Molly A Srour, Mohammad S Siddiqui, Amon Asgharpour, David J Hayes, Neal C Foster, David W Salzman, Arun J Sanyal
Published: 202510.3350/cmh.2025.0933
Abstract
Background & Aims: MicroRNA isoforms (isomiRs) broaden the regulatory landscape of canonical microRNAs, but their role in metabolic dysfunction-associated steatotic liver disease (MASLD) remains unknown. We aimed to characterize the hepatic isomiR la…
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