Haematologica
CSF1R modulates megakaryopoiesis by targeting RUNX1 in immune thrombocytopenia.
Haohao Han, Meng Zhou, Jiaqian Qi, Xiaofei Song, Xueqian Li, Ziyan Zhang, Tingting Pan, Xiaoyan Xu, Mengting Guo, Depei Wu, Yue Han
Published: 202510.3324/haematol.2025.288511
Abstract
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by platelet destruction and defective megakaryopoiesis. However, the mechanisms underlying megakaryocyte (MK) dysfunction in ITP remain unclear. To address this, we perfor…
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