The first known case of Nocardia wallacei infection in Cyprus.

Aim: To present the first known case of Nocardia (N.) wallacei infection in Cyprus. Method: This case report describes the first known N. wallacei infection in Cyprus, diagnosed in a 77-year-old man with underlying pulmonary disease, along with the diagnostic workup and treatment. Discussion: N. wallacei is a rare subtype of Nocardia spp. with about 14 cases reported in literature. It equally affects immunocompromised as well as immunocompetent patients, causing both pulmonary and extrapulmonary symptoms (CNS, skin). First-line treatment includes trimethoprim/sulfamethoxazole (TMP/SMX), but there are trends of global resistance. Conclusion: N. wallacei has rarely been reported as a cause of infection and this is the first known case reported in Cyprus.