Emerging infectious diseasesHumansUtahTularemiaFemaleInfant
Case of Congenital Tularemia with Neuroinvasive Disease, Utah, USA.
Brent D Nelson, Amara Finch, Krow Ampofo, Elizabeth L Ryals, Andrew T Pavia, Anne J Blaschke, Jody L Lin, Benjamin Kalm, Angie White, Kacy D Nowak, Julian A Villalba, Julu Bhatnagar, Bert Lopansri, Elizabeth D Knackstedt
Published: 202510.3201/eid3112.250703
Abstract
Open AccessWe diagnosed neuroinvasive tularemia in a neonate in Utah who had culture-negative pleocytosis in cerebrospinal fluid, rim-enhancing lesions on brain magnetic resonance imaging, and blood microbial cell-free DNA Francisella tularensis detection. Maternal history, serologic testing, and Francisella sp. identified in the fallopian tube by immunohistochemistry and 16S rRNA gene PCR strongly support congenital infection.