Journal of integrative neuroscienceAnimalsAlzheimer DiseaseAmyloid beta-Protein PrecursorDisease ModelsAnimal
The Icelandic Mutation in the Murine APP Gene, mAPPA673T, on Amyloid-β Plaque Burden in the 5×FAD Alzheimer Model.
Anne Anschuetz, Renny Listyono, Thomas Vorley, Bettina Platt, Charles R Harrington, Gernot Riedel, Karima Schwab
Published: 202610.31083/JIN48581
Abstract
BACKGROUND: The protective Icelandic mutation in the amyloid precursor protein (APP) gene, APPA673T, identified in Icelandic and other Nordic populations is associated with a significantly lower risk of developing Alzheimer's disease (AD). Conflictin…
Preview only. Read the full abstract at the source