Journal of integrative neuroscienceOxidopaminePhosphodiesterase 4 InhibitorsHumansCell SurvivalNeuroprotective Agents
Roflupram Reduces 6-OHDA-Induced Cellular Damage in SH-SY5Y Cells by Inhibiting PDE4.
Jiahong Zhong, Xihui Yu, Junling Xue, Qiuming Wang, Zhuomiao Lin
Published: 202610.31083/JIN45490
Abstract
BACKGROUND: The main symptoms of Parkinson's disease (PD) include olfactory impairment and tremor. Current treatment methods for PD generally have limitations such as short duration and severe side effects. The novel phosphodiesterase 4 (PDE4) inhibi…
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