Frontiers in bioscience (Landmark edition)AnimalsMyopiarho-Associated KinasesEpithelial-Mesenchymal TransitionSignal Transduction
TGF-β/RhoA/ROCK Signaling Activation Orchestrates Ciliary Body EMT and Fibrosis in Myopia.
Xuewei Yin, Yixian Hao, Zhongyu Ma, Yunxiao Xie, Bo Bao, Huixia Wei, Qiuxin Wu, Tuling Li, Jiawen Hao, Xuan Zhang, Hongsheng Bi, Dadong Guo
Published: 202610.31083/FBL46605
Abstract
BACKGROUND: Dysregulation of the transforming growth factor (TGF)-β/Ras homolog family member A (RhoA)/Rho-associated protein kinase (ROCK) pathway can lead to fibrotic changes in ocular diseases. The present study investigated its role in epithelial…
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