Frontiers in bioscience (Landmark edition)ApoptosisLignansHumansPolycyclic CompoundsTemozolomide
Combined Schisandrin B and Temozolomide Treatment Induces Mitochondrial Apoptosis in Glioma Cells.
Zebo Tang, Chaoran Guo, Na Wen, Hong Jin, Yuan Dong, Bo Xu, Xiangyu Ma, Liu Han, Jianxin Liu
Published: 202510.31083/FBL46410
Abstract
BACKGROUND: Temozolomide (TMZ) is a standard chemotherapeutic agent for glioma, but prolonged use frequently leads to drug resistance, reducing its therapeutic efficacy. Schisandrin B (Sch B), a lignan isolated from Schisandra chinensis, demonstrates…
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