Frontiers in bioscience (Landmark edition)AnimalsSmad3 ProteinTransforming Growth Factor beta1PolysaccharidesSignal Transduction
Astragalus Polysaccharide Improves Myocardial Fibrosis in Hypertrophic Cardiomyopathy Through the TGF-β1/Smad3 Signal Pathway.
Nana Qin, Wenjun Wu, Baoyin Li
Published: 202510.31083/FBL45595
Abstract
BACKGROUND: Myocardial fibrosis is a key pathological driver of Hypertrophic Cardiomyopathy (HCM), contributing to adverse remodeling and poor prognosis. The transforming growth factor-β1/Smad3 (TGF-β1/Smad3) signaling cascade plays a central role in…
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