Journal of the American Association for Laboratory Animal Science : JAALAS
Effects of Scruff Restraint and Handling-Tail and Tunnel-on Plasma Corticosterone in Female BALB/c Mice (Mus musculus).
Jun Otsuka, Gaku Wagai, Masao Togao, Yuki Ohta-Takada, Minoru Ando, Koji Kawakami
Published: 202610.30802/AALAS-JAALAS-25-134
Abstract
Tunnel handling is a widely recommended, less-aversive method for improving laboratory mouse welfare by reducing handling-induced anxiety. While its effects on behavioral tests and physiologic outcomes have been reported, little is known about its im…
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