Journal of nuclear medicine : official publication, Society of Nuclear MedicineRadiometryKidneyRadiopharmaceuticalsMonte Carlo MethodHumans
A Computational Multinephron Model for Small-Scale Preclinical Renal Dosimetry in Radiopharmaceutical Therapy.
Michelle Andersson, Nicolas Goudin, Marco Pontoglio, Nick Reynaert, Hugo Levillain, Clarita Saldarriaga Vargas
Published: 202610.2967/jnumed.125.270151
Abstract
Nonuniform radiopharmaceutical uptake in kidney tissues leads to substructure-level absorbed dose heterogeneity, confounding the establishment of absorbed dose-effect relationships for nephrotoxicity in radiopharmaceutical therapy. We developed a mod…
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