Spinal myxopapillary ependymoma with anaplastic features: A case report and review of the literature.
Reem Shihab, Muhammad Takhman, Hanood Abu Rass, Othman Othman, Mohsen Yaish
Abstract
Open AccessBackground: Spinal myxopapillary ependymomas (MPEs) are a rare subtype of ependymomas that typically arise in the conus medullaris, cauda equina, and filum terminale, most commonly affecting adults aged 30-50 years and usually located in the lumbosacral spine. Anaplastic MPEs are an even rarer, more aggressive variant that often present at a younger age than conventional MPEs. Case Description: We report a 20-month-old male who presented with a two-week history of abnormal gait and neck stiffness and was diagnosed with anaplastic MPE. Conclusion: This case adds to the limited pediatric literature on anaplastic MPE and underscores the importance of early recognition, thorough histopathological evaluation, and long-term follow-up.