TFE3-rearranged renal cell car cinoma with massive calcification: Imaging-pathologic correlation.

Transcription Factor E3 (TFE3)-rearranged renal cell carcinoma (RCC) is rare. Radiologically, TFE3-rearranged RCC typically appears as a hyperattenuating mass with calcifications. Calcifications typically appear as small punctate or irregular coarse deposits, which are pathologically associated with granular and collagenous stromal degeneration. Here, we report a case of TFE3-rearranged RCC with extensive calcification in a young female, emphasizing imaging-pathologic correlation to enhance diagnostic accuracy. This case underscores the importance of recognizing atypical radiological features in rare RCC subtypes.