Advances in Risk Management and Screening for Women at Increased Risk of Breast Cancer: The Role of MR Imaging and Personalised Approaches.

This review focuses on the management of women at high risk for breast cancer, particularly those with pathogenic variants in BRCA1 and BRCA2, who face elevated lifetime risks. We explore preventive strategies such as risk-reducing surgeries and enhanced screening methods, including MRI. MRI has proved to be an effective tool in early cancer detection, particularly in high-risk populations, and represents a shift toward more personalized and precise screening protocols. Considering the rise in awareness and progress in genetic testing, there is a growing demand for tailored screening methods that balance efficacy, accessibility, and sustainability. Technological advances have resulted in the availability of a range of screening options, and this review highlights the potential for continued innovation in clinical practice and the adoption of strategies that take individual risk factors into account to improve long-term outcomes in breast cancer management.