Zoological researchGliomaCellular SenescenceFatty AcidsAnimalsCarnitine O-Palmitoyltransferase
Tau impedes glioma progression by enhancing fatty acid β-oxidation-induced cellular senescence.
Wan-Hong Han, Wu-Jie Zhao, Jia-Wei He, Wen-Peng Zhao, Han-Wen Lu, Zhen-Wei Lu, Xian-Sheng Qiu, Chen Chang, Ya-Ya Zhang, Yuan-Yuan Xie, Yan-Yan Geng, Bing-Chang Zhang, Zhan-Xiang Wang
Published: 202510.24272/j.issn.2095-8137.2025.066
Abstract
Tau ( MAPT) expression is inversely associated with glioma malignancy and patient survival. However, the molecular mechanisms underlying this correlation are yet to be fully investigated. This study demonstrated that tau suppressed glioma cell prolif…
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