DiabetesAnimalsMechanistic Target of Rapamycin Complex 1LiverMiceGlucose
Novel Function of Osteoprotegerin in the Modulation of Glucose Metabolism in the Liver via mTORC1.
Sheng Qiu, Xia Wang, Ke Li, Siliang Zhang, Yerui Lai, Qiao Mi, Min Yang, Dongfang Liu, Ling Li, Qinan Wu, Mengliu Yang
Published: 202510.2337/db25-0207
Abstract
Osteoprotegerin (OPG) has emerged as a pivotal factor in metabolic disease pathology; however, its role in hepatic glucose metabolism remains poorly understood. We demonstrated a pronounced reduction in hepatic OPG expression in obese mice, attributa…
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