The Bulletin of Tokyo Dental CollegePorphyromonas gingivalisOxidative StressHumansSigma FactorBacterial Proteins
SigH of Porphyromonas gingivalis Regulates Oxidative Stress Resistance and Invasion of Oral Epithelial Cells.
Yuichiro Kikuchi, Eitoyo Kokubu, Hideo Yonezawa, Kazuyuki Ishihara
Published: 202510.2209/tdcpublication.2025-0013
Abstract
Porphyromonas gingivalis, a key periodontal pathogen, employs extra-cytoplasmic function (ECF) sigma factors to adapt to the dynamic oral environment and establish chronic infection. Among these, PGN_1740 (SigH) has been implicated in oxidative stres…
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