JMIR public health and surveillanceHumansAntipsychotic AgentsMaleRetrospective StudiesFemale
Comparison of In Vitro Metrics With Real-World Risk of Drug-Induced Parkinsonism Due to Antipsychotic Drugs: Retrospective Cohort Study.
Woo-Taek Lim, Hyun Woo Lee, Seungyeon Kim, Kwangsoo Kim, Yong Min Ahn, Minseok Hong, Yun Mi Yu, Ha Young Jang
Published: 202610.2196/81876
Abstract
Background: Drug-induced parkinsonism (DIP) predominantly occurs due to antipsychotic drugs (APDs) blocking dopamine D2 receptors (D2Rs). However, in vitro assays often fail to fully reflect real-world variability in clinical outcomes. Objective: Thi…
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