CNS & neurological disorders drug targets
Investigation of the Antiepileptic and Anti-inflammatory Effects of Empagliflozin on Penicillin-induced Epileptiform Activity in Rats.
Mehmet Kayhan, Ayhan Cetinkaya, Merve Uzuner
Published: 202610.2174/0118715273423680251125073602
Abstract
INTRODUCTION: Sodium-glucose transport protein 2 (SGLT-2) inhibition regulates neuronal excitability by shifting glucose metabolism toward ketone utilization and by reducing oxidative stress and inflammation. Based on these mechanisms, this study inv…
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