Anti-inflammatory & anti-allergy agents in medicinal chemistry
Clinical Applications of Ligand Traps Targeting Activin Type II Receptors.
Kunihiro Tsuchida
Published: 202610.2174/0118715230416604251029062751
Abstract
This review summarizes recent advances in ligand trap therapies targeting activin type II receptors [ActRIIA/ACVR2A and ActRIIB/ACVR2B], which serve as shared receptors for members of the TGF-β family, including activins, GDF11, and myostatin [MSTN].…
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