Anti-cancer agents in medicinal chemistry
Molecular Simulation, Pharmacophore Mapping, and 3D QSAR Modeling on Chromene-Based SERDs.
Suresh Thareja, Sanjana Bisht
Published: 202610.2174/0118715206425764251107012953
Abstract
INTRODUCTION: Estrogen receptor (ERα) is known to be a legitimate therapeutic target for the treatment of ER-positive breast cancer. Although selective estrogen receptor degraders (SERDs) like fulvestrant suppress ER signaling, their limited bioavail…
Preview only. Read the full abstract at the source