Anti-cancer agents in medicinal chemistry
ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification of Small-Molecule Inhibitors.
Hesham M Hassan, Waleed K Abdulsahib, Hassan M Otifi, Mohammed A Alshehri, Mohamed O Andarawi, Khaled M Darwish, Sameh S Elhady, Dalal Sulaiman Alshaya, Hanadi A Katouah, Aiysha Althobaiti, Eman Fayad, Muhammad Alaa Eldeen
Published: 202510.2174/0118715206395527250902101008
Abstract
INTRODUCTION: Glycosylation plays a crucial role in cellular processes such as recognition and signaling, and its dysregulation is associated with tumor progression. Alpha-1,3-mannosyltransferase (ALG3) is a key enzyme in N-glycosylation, and its abe…
Preview only. Read the full abstract at the source