Medicinal chemistry (Shariqah (United Arab Emirates))
Diaryl Ether Derivatives as Dual Inhibitors of Selective COX-2 and EGFR: Synthesis, In silico, and In Vitro Analysis.
Vivekananda Saha, Aynal Hoque, Abbas Ali, Souvik Sarkar, Prasun Kanti Pradhan, Soma Das Pradhan, Goutam Biswas
Published: 202610.2174/0115734064421626251114091432
Abstract
INTRODUCTION: The rising prevalence of cancers with chronic inflammation is a leading global health concern. Modern anticancer treatments require dual inhibitors of cyclooxygenase- 2 (COX-2) and Epidermal Growth Factor Receptor (EGFR) with minimal ad…
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