Medicinal chemistry (Shariqah (United Arab Emirates))PiperidinesAntitubercular AgentsHumansMolecular Docking SimulationMicrobial Sensitivity Tests
Synthesis, Docking, and Biological Studies of Pyrazine Derivatives as Antimycobacterial Agents.
Nagaraja Reddy Gangarapu, Archakam Ranganatham, Eeda Koti Reddy, Chakka Kiran Kumar, Shivaraj Yellappa, Kothapalli Bannoth Chandrasekhar, Elanchezhiyan Manickan
Published: 202510.2174/0115734064337815241115050020
Abstract
INTRODUCTION: A series of novel 2-((3,5-diphenylpyrazin-2-yl)amino)-1-(piperidin-1- yl/pyrrolidin-1-yl)ethanone derivatives (5a-5l) were synthesized and evaluated for their tuberculosis activity using the standard strain H37Rv and two other clinicall…
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