Current molecular medicine
SIRT6 Relieves Acute Lung Injury by Enhancing PGC-1α Expression and Improving Mitochondrial Function.
Xiangyun Li, Yanshuai Mo, Jia Shi, Shasha Liu, Shasha Bu, Huayang Liu, Wenxing Li, Jianbo Yu
Published: 202510.2174/0115665240423301250929091606
Abstract
INTRODUCTION: Sepsis-induced acute lung injury (ALI) is closely related to the dysfunction of mitochondria. Sirtuin 6 (SIRT6), as a nicotinamide adenine dinucleotide (NAD+)-dependent protein deacylase, is involved in several cellular processes. Howev…
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