Current molecular medicine
Molecular Pathways and Recent Therapeutic Strategies for Polyglutamine Diseases.
Sagor Kumar Roy, Ashima Barman, Seidu A Richard, Bijal Arvinkumar Lacmane
Published: 202510.2174/0115665240393446250829084646
Abstract
The abnormal expansion of trinucleotide cytosine-adenine-guanine [CAG] repeats within disease-associated genes is the primary cause of polyglutamine [polyQ] diseases. This study aims to evaluate the pathological threshold at which the polyglutamine […
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