Current gene therapy
Foxp3+ Tregs Promote M2 Macrophage Polarization via Sirt1-ERK1/2-STAT3 Pathway in Ovarian Cancer Progression.
Nai Liang, Hui Chen, Yi Yang, Benlong Guo, Zehai Xu, Li Li, Yunfeng Jin
Published: 202510.2174/0115665232417125251021114250
Abstract
INTRODUCTION: Epithelial Ovarian Cancer (EOC) is a highly aggressive gynecological malignancy with a high mortality rate primarily due to late-stage diagnosis and metastatic dissemination. Regulatory T cells (Tregs) have emerged as critical mediators…
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