Current medicinal chemistry
Exploring the Regulatory Effects of Curcumin on CD47-Overexpressing Esophageal Cancer Cells via Network Pharmacology with Preclinical Validation.
Yan Kang, Xiao Li, Hongchao Zhen, Jing Wang, Haishan Lin, Bangwei Cao
Published: 202610.2174/0109298673422903251129071114
Abstract
INTRODUCTION: Esophageal cancer(EC) is a significant clinical challenge due to its aggressiveness and poor prognosis. CD47, a transmembrane protein, inhibits macrophage phagocytosis and is linked to tumor advancement and poor outcomes. The interactio…
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