Current medicinal chemistry
New SufA Protease Inhibitors and Activity-based Probes: Design, Synthesis, and Antibacterial Activity Assessment.
Ewa Burchacka, Karol Postawa, Paweł Pięta
Published: 202610.2174/0109298673418188251128105425
Abstract
BACKGROUND: The growing threat of bacterial drug resistance compels researchers to pursue new therapeutic strategies. Finegoldia magna secretes SufA, a subtilisin- like protease that plays a critical role in virulence by degrading host defense molecu…
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