Current medicinal chemistry
Synthesis of Enduracididine Free Linear Teixobactin Analogs: Molecular Docking, DFT Calculations, and Their Antimicrobial Activities, Bacterial Cell Wall Lysis and Glucose Assay.
Kumari Dalli, Trimurthulu Sadhanala, Nagendra Govindappa, Gouthami Kuruvalli, Damodara Reddy Vaddi, Aravinda Thippa Reddy, Gururaj Kudur Jayaprakash
Published: 202610.2174/0109298673382051251001045242
Abstract
INTRODUCTION: Teixobactin (TX) is a new class of antibiotics with a unique structure and strong efficacy against gram-positive bacteria. It is a "head-to-side-chain" cyclodepsipeptide with considerable potential as a lead molecule for creating novel…
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