Current medicinal chemistry
RTK AXL and its Isoforms: Regulation and Implications in Cancer.
Ilona Malikova, Aizhan Syzdykova, Nazia Islam, Marina Kriajevskaia, Eugene Tulchinsky
Published: 202610.2174/0109298673382005250828124053
Abstract
As a member of the TAM family of receptor kinases, the AXL protein plays an essential role in biological processes that maintain tissue homeostasis. Deregulated AXL signalling in tumour cells is linked to cancer progression, poor prognosis, metastasi…
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