Current medicinal chemistry
Side Chain Effects on the Lipophilicity-antimicrobial-toxicity Correlation of Greener 4-Alkoxy/Amino-7-Chloroquinolines.
Gabriela F Fiss, Everton P Silva, Maria F S Madruga, Abraão P Sousa, Helivaldo D S Souza, Rádamis B Castor, Maria H Nascimento, Krystyna G Lira, Petrônio F Athayde-Filho
Published: 202510.2174/0109298673372039250614231629
Abstract
BACKGROUND: More robust 4-substituted 7-chloroquinolines have been investigated for their diverse properties. However, there is still no systematic study that correlates the effects of the side chain at the 4-position of chloroquine and hydroxychloro…
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