The Impact of Nutritional Management on Postoperative Recovery Outcomes in Prostate Cancer Patients Undergoing Radical Prostatectomy: A Retrospective Study.
Guoyu Du, Yi Zhang
Abstract
Open AccessBackground: Prostate cancer remains a prevalent malignant tumor among males globally, while the impact of perioperative nutritional management on prognosis remains poorly defined. This study aims to investigate the management efficacy of dietary supplement (nutrient) administration in prostate cancer patients following radical prostatectomy. Methods: A retrospective analysis was conducted on clinical data from 70 prostate cancer patients who underwent radical prostatectomy at our institution between March 2022 and January 2024. Participants were divided into two groups based on distinct perioperative management protocols: the control group received conventional management, while the observation group received targeted dietary supplements (nutrients) in addition to the conventional regimen. Comparative analyses were performed on clinical indicators, recovery parameters, and adverse symptom incidence between groups to evaluate the role of nutrient supplementation in perioperative management. Results: Baseline characteristics demonstrated comparability between groups (P>0.05). The observation group exhibited significantly shorter postoperative drainage tube removal duration and hospital stay compared to controls (P<0.05). First postoperative bowel movement time and independent ambulation recovery time were also reduced in the observation group (P<0.05). No statistically significant difference in BMI levels was observed between groups (P>0.05). Serum albumin levels measured at preoperative day 1, and postoperative days 1 and 3 were significantly elevated in the observation group (P<0.05). Postoperative day 3 serum immunoglobulin levels (IgG, IgA, IgM) showed marked increases in the observation group (P<0.05). The observation group reported significantly fewer gastrointestinal symptoms including thirst, hunger, and nausea compared to controls (P<0.05). Conclusion: Dietary supplement (nutrient) administration may improve perioperative nutritional parameters, enhance systemic immunity, facilitate postoperative rehabilitation, and alleviate gastrointestinal symptoms in prostate cancer patients.