Exploring the Combination of Traditional Chinese and Allopathic Medicine in the Treatment of Polycystic Ovary Syndrome from the Perspective of Modern Medicine.
Xiang Hu, Mingya Zhu, Qin Zhou, Zimo Li, Liping Luo, Wanzhi Liang, Shujun Chen, Xingwei Pu, Juan Du
Abstract
Open AccessPolycystic ovary syndrome (PCOS) is a prevalent and multifaceted endocrine disorder characterized by hyperandrogenism, ovarian dysfunction, and insulin resistance. This review aims to synthesize current evidence from both allopathic medicine and Traditional Chinese Medicine (TCM) to clarify the pathophysiological mechanisms of PCOS and evaluate the therapeutic potential of integrative management strategies. We first outline key epidemiological, genetic, and hormonal features that underpin PCOS, with particular emphasis on insulin resistance, chronic inflammation, and dysregulated gonadotropin secretion. We then summarize core TCM treatment principles and describe how herbal medicine, acupuncture, and combined therapies modulate endocrine pathways, improve metabolic homeostasis, and regulate immune-inflammatory responses. Clinical studies further suggest that TCM-based interventions may enhance ovulatory function, improve metabolic parameters, and alleviate hyperandrogenic symptoms, supporting their complementary role alongside allopathic treatments. Finally, current limitations-including variability in TCM pattern diagnosis, heterogeneity of herbal preparations, and methodological constraints in mechanistic research-are highlighted to guide future investigations. Overall, this review underscores the clinical relevance and potential value of integrative approaches that bridge traditional and modern medical frameworks in the comprehensive management of PCOS.