Food and Beverage Habits Among Individuals with Primary Hyperhidrosis: A Case-Control Survey in Sweden.

Aim: Excessive sweat production in primary hyperhidrosis (PH) can lead to water and mineral loss, yet data on patients' dietary habits are limited. Purpose: To explore associations between food and beverage consumption and severe PH. Patients and Methods: Participants with primary palmar and axillary hyperhidrosis (n=171) and without hyperhidrosis (n=165) completed a validated questionnaire on food and beverage habits at two hospitals in northern Sweden. Frequency and quantity of specific foods and beverages were compared between groups. Results: A total of 336 individuals participated in this study (men, n=109; women, n=218; unspecified sex, n=9). Individuals with PH were younger (18-29 years, n=104 vs n=66; p<0.001) and more frequently female compared to controls (n=75 vs 58; p<0.001). Total caffeine consumption was higher in PH (median score: 186.6 vs.151.0; p<0.001), and 57% of individuals with PH consumed energy drinks weekly compared with 39.5% of controls (p<0.001). Spicy foods, fatty foods, fast foods, and sweets were reported to trigger sweating. Women with PH more often reported difficulties replenishing water loss, and increased thirst was the most reported symptom in both men and women. Conclusion: PH was associated with higher caffeine intake, distinct beverage consumption patterns, and self-reported fluid loss symptoms. These findings indicate potential associations between diet and PH and may inform patient education and future research, although causality cannot be inferred from this study.