The Journal of toxicological sciencesAnimalsDogsVacuolesAdrenal CortexMale
Pathological features of the recovery phase in drug-induced vacuolar lesions caused by steroidogenesis disruption in the canine adrenal cortex.
Ryo Daniel Obara, Yuki Kato, Yoshiji Asaoka, Hiroyuki Oka, Yukie Murata, Takeshi Izawa, Mitsuru Kuwamura
Published: 202610.2131/jts.51.57
Abstract
Steroidogenesis disruption caused by compounds causes vacuolar lesions in the adrenal cortex. However, research on the reversibility of compound-induced adrenal lesions remains limited. In a 4-week oral repeated-dose toxicity study with a 4-week reco…
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