The Journal of toxicological sciencesAnimalsProtein BindingHumansBlood ProteinsChlorpromazine
Evaluation of toxicokinetic interactions mediated by plasma protein binding during amoxapine intoxication.
Akifumi Okamoto, Yoshitaka Yamazaki, Natsumi Hattori-Usami, Kenji Momo, Asuka Kaizaki-Mitsumoto, Satoshi Numazawa
Published: 202610.2131/jts.51.31
Abstract
Toxicity enhancement mediated by plasma protein binding during intoxication remains poorly understood. It is known that in mice, brain penetration of amoxapine (AMX) increases nonlinearly with increasing doses; therefore, this study investigated its…
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