The Journal of bone and joint surgery. American volume
Cefazolin and the R1 Side Chain: Why Patients with a Cephalosporin Allergy Can Be Safely Given Cefazolin While Undergoing Joint Arthroplasty.
Josef E Jolissaint, Katherine E Mallett, Andrew L Thomson, Alberto V Carli, Matthew S Austin
Published: 202610.2106/JBJS.25.01349
Abstract
BACKGROUND: Cefazolin, a first-generation cephalosporin, is the standard antibiotic for perioperative prophylaxis in patients undergoing hip or knee arthroplasty. Research has demonstrated significantly higher periprosthetic joint infection (PJI) rat…
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