Dental and medical problemsHumansSleep Initiation and Maintenance DisordersSleep ApneaObstructivePhenotype
Headache phenotypes in insomnia, obstructive sleep apnea, and COMISA: Impact on diagnosis and therapy.
Miguel Meira E Cruz, Elsa Parreira, Hrayr Attarian
Published: 202510.17219/dmp/207666
Abstract
Headache associated with comorbid insomnia and sleep apnea (COMISA) may represent a distinct clinical phenotype. Its severity, refractoriness and unique characteristics necessitate a comprehensive, integrative therapeutic approach.