Journal of the American Society of Nephrology : JASN
Therapeutic Potential of HSP90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment.
Soo Min Lee, Myoung Seok Lee, Hae Rim Jung, Jeonghwan Lee, Bogyeong Cho, Wencheng Jin, Min Hoan Moon, Nayeon Shin, Seung Hyun Han, Da Som Choi, Bada Lee, Seung-Pyo Hong, Jong-Il Kim, Chun Soo Lim, Sung-Yup Cho
Published: 202610.1681/ASN.0000000975
Abstract
BACKGROUND: Kidney fibrosis is a major pathological feature of chronic kidney disease (CKD), characterized by excessive deposition of extracellular matrix proteins, leading to progressive loss of kidney function. N6-methyladenosine (m6A) RNA methylat…
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