Critical reviews in oncogenesisHumansNeoplasmsProtein Kinase InhibitorsJNK Mitogen-Activated Protein KinasesAntineoplastic Agents
Review Article: Efficacy and Safety of JNK Inhibitors in Cancer Therapy.
Lakkakula Suhasini Sahithi, Poojith Nuthalapati, Mohammed Faiz Hussain, Sirpu Natesh Nagabhishek, Bibi Umeza, Roopa D Santoshi, Khan A K Afzal, Mohan Krishna Ghanta
Published: 202510.1615/CritRevOncog.2025060497
Abstract
The c-Jun N-terminal protein kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family. JNK1, JNK2, and JNK3 are three isoforms encoded by distinct genes. JNK signaling controls a variety of biological functions, such as cell p…
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