Allergologia et immunopathologiaHumansMicroRNAsProto-Oncogene Proteins c-bcl-2MaleMiddle Aged
Effect of miR-1 and miR-126-5p in BCL2 and PIK3R2 regulation in apoptotic signaling during ST-elevation myocardial infarction.
Arshia Mehmood, Almas Muhammad Arshad, Awais Altaf, Tahir Maqbool, Hafiza Saba Safdar, Muhammad Faisal, Madeeha Shahzad Lodhi, Nawal Al-Hoshani, Maher S Alwethaynani, Shaza N Alkhatib, Omniah A Mansouri, Hanan Abdulrahman Sagini
Published: 202610.15586/aei.v54i1.1520
Abstract
ST-elevation myocardial infarction (STEMI) involves the complete blockage of a coronary artery, leading to severe cardiac damage and high mortality. miR-1 promotes cardiomyocyte apoptosis by downregulating the anti-apoptotic protein BCL2, while miR-1…
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