Physiology international
The therapeutic effects of ligustilide in cuprizone-induced sciatic nerve injury in rats via activation of autophagy and inhibition of apoptosis.
Abdulazez N Alqhtani, Abdulrhman A Eid, Malek S Alharbi, Waseem K Bin Nouh, Shatha S Alharbi, Wejdan M A Alghamdi, Meshal M Albalawi, Hanan M Hassan, Mohammed M H Al-Gayyar
Published: 202610.1556/2060.2025.00715
Abstract
Purpose: Ligustilide, an active ingredient from Rhizoma Chuanxiong, exhibits anti-inflammatory, antioxidant, and neuroprotective effects. We aim to evaluate the protective effects of ligustilide against cuprizone-induced sciatic nerve injury in rats…
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