Experimental animals
Dusp5, transcriptionally inhibited by SOX11, inhibits Th2 differentiation in CD4+ T cells: a promising therapeutic target for allergic rhinitis.
Li Jiang, Chunrui Wang, Wei Han, Shijia Xu, Qi Hu
Published: 202510.1538/expanim.25-0076
Abstract
Allergic rhinitis (AR) is an inflammatory disorder driven primarily by aberrant T helper 2 (Th2) differentiation in CD4⁺ T cells. Although dual-specificity phosphatase 5 (DUSP5) has been implicated in inflammatory and autoimmune regulation, its role…
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